When it comes to soft assistive devices — like the wearable exosuit being created by the Harvard Biodesign Lab — the wearer and the robot need to be in sync. But every human moves a bit differently, and tailoring the robot’s parameters to an individual user is a time-consuming and inefficient process.Now, researchers from the Harvard John A. Paulson School of Engineering and Applied and Sciences (SEAS) and the Wyss Institute for Biologically Inspired Engineering at Harvard University have developed an efficient machine-learning algorithm that can do that work quickly.The research is described in Science Robotics.“This new method is an effective and fast way to optimize control parameter settings for assistive wearable devices,” said Ye Ding, a postdoctoral fellow at SEAS and co-first author of the research. “Using this method, we achieved a huge improvement in metabolic performance for the wearers of a hip extension assistive device.”,Human beings constantly tweak their movements to save energy while walking. Researchers call this the metabolic cost.“Before, if you had three different users walking with assistive devices, you would need three different assistance strategies,” said Myunghee Kim, a postdoctoral research fellow at SEAS and the other co-first author. “Finding the right control parameters for each wearer used to be a difficult, step-by-step process.”The new algorithm, developed by researchers led by Conor Walsh, the John L. Loeb Associate Professor of Engineering and Applied Sciences, and Scott Kuindersma, assistant professor of engineering and computer science at SEAS, cuts through that variability to rapidly identify the best control parameters to minimize the work of walking.The researchers applied so-called human-in-the-loop optimization, which uses real-time measurements of human physiological signals, such as breathing rate, to adjust the control parameters of the device. As the algorithm honed in on the best parameters, it told the exosuit when and where to deliver its assistive force to improve hip extension. The Bayesian Optimization approach the team used was first reported in a paper last year in PLOSone.The combination of the algorithm and suit reduced metabolic cost by 17.4 percent compared with walking without the device, an improvement of more than 60 percent over the team’s previous work.“Optimization and learning algorithms will have a big impact on future wearable robotic devices designed to assist a range of behaviors,” said Kuindersma. “These results show that optimizing even very simple controllers can provide a significant, individualized benefit to users while walking. Extending these ideas to consider more expressive control strategies and people with diverse needs and abilities will be an exciting next step.”“With wearable robots like soft exosuits, it is critical that the right assistance is delivered at the right time so that they can work synergistically with the wearer,” said Walsh. “With these online optimization algorithms, systems can learn how to achieve this automatically in about 20 minutes, thus maximizing benefit to the wearer.”The team’s next step is to apply the optimization to a more complex device that assists multiple joints, such as hip and ankle, at the same time.“In this paper, we demonstrated a high reduction in metabolic cost by just optimizing hip extension,” said Ding. “This goes to show what you can do with a great brain and great hardware.”This research was supported by the Defense Advanced Research Projects Agency, Warrior Web Program, the Wyss Institute, and the Harvard John A. Paulson School of Engineering and Applied Science.